Recent major publications from Romee Lab:

1. Engineering innate immune cells for cancer immunotherapy.  Tarannum M, Ding X, Barisa M, Hu S, Anderson J, Romee R*, Zhang J. Nature Biotechnol, 2025, Apr;43(4):516-533. doi: 10.1038/s41587-025-02629-5. Epub 2025 Apr 14. PMID: 40229380. *Co-corresponding author.

2. Nonpathogenic E. coli engineered to surface display cytokines as a new platform for immunotherapy.  Yang S, Sheffer M, Kaplan IE, Wang A, Tarannum M, Dinh K, Abdulhamid Y, Shapiro R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Marquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Chen J, Wu CJ, Barbie D, Li J, Romee R. Nature Biotechnol, 2024, Oct 4 (online ahead of print). PMID: 39367093

3. First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer. Shapiro RM, Sheffer M, Booker MA, Tolstorukov MY, Birch GC, Sade-Feldman M, Fang J, Li S, Lu W, Ansuinelli M, Dulery R, Tarannum M, Baginska J, Dwivedi N, Kothari A, Penter L, Abdulhamid YZ, Kaplan IE, Khanhlinh D, Uppaluri R, Redd RA, Nikiforow S, Koreth J, Ritz J, Wu CJ, Soiffer RJ, Hanna GJ, Romee R. J Hematol Oncol. 2025 Feb 14;18(1):17. doi: 10.1186/s13045-025-01669-3.PMID: 39948608 

4. Memory-like NK CAR cells targeting the membrane-proximal domain of mesothelin demonstrate promising activity against ovarian cancer cell lines, patient-derived xenograft explants, and in pre-clinical xenograft mice. Tarannum M, Dinh K, Vergara J, Birch G, Adulhamid YZ, Kaplan IE, Ay O, Maia A, Beaver O, Sheffer M, Shapiro R, Ali AK, Dong H, Ham JD, Bobilev E, Ganapathy S, Chayawatto C, Koreth J, Cloud PP, Gokhale P, Barbie DA, Matulonis UA, Soiffer RJ, Ritz J, Porter RL, Chen J, Romee R. Science Advances, 2024, Jul 12;10(28):eadn0881. Epub 2024 Jul 12. PMID: 38996027.

5. Shapiro RM, Birch GC, Hu G, Vergara Cadavid J, Nikiforow S, Baginska J, Ali AK, Tarannum M, Sheffer M, Abdulhamid YZ, Rambaldi B, Arihara Y, Reynolds C, Halpern MS, Rodig SJ, Cullen N, Wolff JO, Pfaff KL, Lane AA, Lindsley RC, Cutler CS, Antin JH, Ho VT, Koreth J, Gooptu M, Kim HT, Malmberg KJ, Wu CJ, Chen J, Soiffer RJ, Ritz J, Romee R. J Clin Invest, 2022, Jun 1;132(11). PMID: 35349491.

6. Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia. Dong H, Ham JD, Xie G, Vergara J, Ali A, Tarannum M, Donner H, Baginska J, Abdulhamid Y, Dinh K, Soiffer RJ, Ritz J, Glimcher LH, Chen J, Romee R. Proct Natl Acad Sci USA (PNAS), 2022, Jun 21;119(25): e2122379119. PMID: 35696582, PMCID: PMC9231490.
​
Full list of publications:

https://pubmed.ncbi.nlm.nih.gov/?term=romee+r&sort=date